hrp0089p1-p266 | Thyroid P1 | ESPE2018

Childhood Thyroid Autoimmunity and Relation to Islet Autoantibodies in Children at Risk for Type 1 Diabetes

Jonsdottir Berglind , Larsson Christer , Jonsson Ida , Lundgren Markus , Larsson Helena

Background: The aim was to determine prevalence and age at seroconversion of thyroid autoimmunity and relation to islet autoantibodies, gender and HLA-DQ genotypes in children followed from birth because of increased genetic risk for type 1 diabetes.Methods: In 1874 10-year-old children followed in the Diabetes Prediction in Skåne (DiPiS) study, blood samples were analysed for autoantibodies against thyroid peroxidase (TPOAb), thyroglobulin (TGAb), ...

hrp0086p1-p216 | Diabetes P1 | ESPE2016

Thyroid and Islet Autoantibodies Predict Autoimmune Thyroid Disease Already at Diagnosis of Type 1 Diabetes

Jonsdottir Berglind , Larsson Christer , Carlsson Annelie , Forsander Gun , Anders Ivarsson Sten , Lernmark AEke , Ludvigsson Johnny , Marcus Claude , Samuelsson Ulf , Ortqvist Eva , Elding Larsson Helena

Background: Screening for autoimmune thyroid disease in children and adolescents with type 1 diabetes lacks consensus. Optimal screening methods should benefit the patients and reduce costs to healthcare.Objective and hypotheses: To, at diagnosis of type 1 diabetes, determine the predictive value of thyroid autoantibodies, thyroid function, islet autoantibodies, and HLA-DQ for autoimmune thyroid disease.Method: At diagnosis of type...